Ductal carcinoma in situ (DCIS) means the cells that line the milk ducts of the breast have become cancer, but they have not spread into surrounding breast tissue. DCIS is considered non-invasive or pre-invasive breast cancer.
Is ductal carcinoma in situ benign or malignant?
If these abnormal cells, which are uncontrollably growing, stay inside the duct, they are referred to as Ductal Carcinoma In-Situ (DCIS). They are ductal cells that have become malignant, but they have remained in their original place (in-situ) and are thus a noninvasive cancer.
Is carcinoma in situ really cancer?
Carcinoma in situ refers to cancer in which abnormal cells have not spread beyond where they first formed. The words “in situ” mean “in its original place.” These in situ cells are not malignant, or cancerous. However, they can sometime become cancerous and spread to other nearby locations.
What is the survival rate for ductal carcinoma in situ?
Generally, patients diagnosed with DCIS have an excellent long-term breast-cancer-specific survival of around 98% after 10 years of follow -up24–27 and a normal life expectancy.
How serious is DCIS cancer?
DCIS isn’t life-threatening, but having DCIS can increase the risk of developing an invasive breast cancer later on. When you have had DCIS, you are at higher risk for the cancer coming back or for developing a new breast cancer than a person who has never had breast cancer before.
What stage is ductal carcinoma in situ?
DCIS is also called intraductal carcinoma or stage 0 breast cancer. DCIS is a non-invasive or pre-invasive breast cancer. This means the cells that line the ducts have changed to cancer cells but they have not spread through the walls of the ducts into the nearby breast tissue.
How fast does ductal carcinoma in situ grow?
It assumes that all breast carcinomas begin as DCIS and take 9 years to go from a single cell to an invasive lesion for the slowest growing lesions, 6 years for intermediate growing DCIS lesions, and 3 years for fast-growing DCIS lesions.
What will happen if ductal carcinoma in situ is not treated?
If DCIS is not treated, the cancer cells may develop the ability to spread outside the ducts, into the surrounding breast tissue. This is known as invasive breast cancer. Invasive cancer has the potential to also spread to other parts of the body.
Are there other forms of carcinoma in situ?
Meaning of Carcinoma In Situ The subtypes of carcinomas include adenocarcinoma, squamous cell carcinoma, transitional cell carcinoma (in the bladder or kidneys), and basal cell carcinoma.
Can DCIS spread after biopsy?
Because DCIS is not an invasive cancer and cannot spread to other parts of the body, whole body treatments, like chemotherapy, are not indicated for this stage of disease.
Can DCIS lead to other cancers?
In some cases, DCIS may become invasive cancer and spread to other tissues. At this time, because of concerns that a small proportion of the lesions could become invasive, nearly all women diagnosed with DCIS currently receive some form of treatment.
Is ductal carcinoma in situ curable?
Women diagnosed with DCIS have very good prognoses. Ten years after DCIS diagnosis, 98% to 99% of women will be alive. Based on this good prognosis, DCIS usually is treated by lumpectomy followed by radiation therapy. If the DCIS is large, a mastectomy may be recommended.
Is ductal carcinoma in situ fatal?
DCIS (ductal carcinoma in situ) is the most common form of non-invasive breast cancer and is considered stage 0 cancer. While DCIS isn’t considered life threatening, it does increase the risk of developing invasive breast cancer later in life.
Is DCIS grade 3 bad?
High Grade DCIS: May also be referred to as Nuclear Grade 3 or ‘high mitotic rate’. In this case, the cancer cells look more abnormal and tend to be fast-growing and more likely to recur after surgery.
Is DCIS cancer or precancer?
DCIS is considered a pre-cancer because sometimes it can become an invasive cancer. This means that over time, DCIS may spread out of the ducts into nearby tissue, and could metastasize. Currently, there’s no good way to predict which will become invasive cancer and which won’t.
What are the chances of getting DCIS in the other breast?
After a DCIS diagnosis in one breast, the average risk of developing either DCIS or invasive breast cancer in the OPPOSITE breast is small — under 1% each year. The risk is higher for women who have an abnormal breast cancer gene (BRCA1 or BRCA2).