Question: What Is An Acell Graft?

ACell (ACell, Inc.) is one of the newest xenograft biological dermal substitutes composed of extracellular matrix (ECM) derived from porcine urothelium that is lyophilized and dehydrated.

Is ACell synthetic?

ACell’s non-synthetic, fully-resorbable devices are minimally processed to remove cellular content and mitigate the inflammatory response1,8.

What is ACell Cytal?

Cytal Burn Matrix is a medical device manufactured using ACell’s proprietary MatriStem UBM™ (Urinary Bladder Matrix) technology. The device maintains an intact epithelial basement membrane and facilitates the body’s ability to remodel site-appropriate tissue1.

What makes a cell ACell?

In biology, the smallest unit that can live on its own and that makes up all living organisms and the tissues of the body. A cell has three main parts: the cell membrane, the nucleus, and the cytoplasm. A cell is surrounded by a membrane, which has receptors on the surface.

What is Cytal made of?

Cytal® Wound Matrix Devices Comprised of naturally-occurring urinary bladder matrix (UBM), these products maintain an intact epithelial basement membrane. Cytal devices are appropriate for acute wounds and chronic wounds.

Is ACell a stem cell?

Stem cells are present in all tissues in the human body. When activated by an acellular device, such as ACell’s MatriStem® (an FDA-approved medical device), stem cells recruit other cell types to the area and trigger tissue regeneration.

How do you use Epifix graft?

EPIFIX® can be hydrated while on the wound site with sterile saline solution. Simply apply several drops of sterile solution to EPIFIX®. During and following hydration, the embossment on EPIFIX® will begin to fade. EPIFIX® should be placed on the wound site, using the orientation of the embossment lettering as a guide.

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What is urinary bladder matrix?

Urinary bladder matrix (UBM) is an acellular, noncross-linked, resorbable, biologically-derived extracellular matrix (ECM) scaffold that can aid in establishing a neovascularized wound bed in certain wounds.

Is ACell a public company?

ACell is offering 5,000,000 shares of its common stock at an expected initial public offering price between $14.00 and $16.00 per share. ACell has applied to list its common stock on the Nasdaq Global Market under the ticker symbol “ACLL.”

What are the 4 stages of the cell cycle?

In eukaryotes, the cell cycle consists of four discrete phases: G1, S, G2, and M. The S or synthesis phase is when DNA replication occurs, and the M or mitosis phase is when the cell actually divides. The other two phases — G1 and G2, the so-called gap phases — are less dramatic but equally important.

Why is an organelle important?

Organelles are specialized structures that perform various jobs inside cells. The term literally means “little organs.” In the same way organs, such as the heart, liver, stomach, and kidneys, serve specific functions to keep an organism alive, organelles serve specific functions to keep a cell alive.

What are the 4 major functions all cells perform?

Answer: They provide structure and support, facilitate growth through mitosis, allow passive and active transport, produce energy, create metabolic reactions and aid in reproduction.

How are MatriStem urinary bladder matrix UBM products terminally sterilized?

The device is terminally sterilized using electron-beam irradiation. The MatriStem UBM Pericardial Patch is intended for the reconstruction and repair of the pericardium.

What is MatriStem?

(1) MatriStem, a parchment-like sheet made from specific layers of pig bladder, is a natural extracellular matrix that can be applied to the site of an injury or damaged skin in order to encourage the body’s own capabilities to repair and restore tissue.

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What is MicroMatrix?

MicroMatrix® is a sterile, porcine-derived, naturally-occurring lyophilized extracellular matrix in particle form that maintains and supports a healing environment for wound management. • Supports a healing environment through constructive remodeling. • Comprised of naturally-occurring urinary bladder matrix.